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Found 1 hit Enz. Inhib. hit(s) with Target = 'Glutamate receptor ionotropic, NMDA 1' and Ligand = 'BDBM50005039'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50005039
PNG
(5,7-Dichloro-4-(1-oxo-1,3-dihydro-isoindol-2-yl)-1...)
Show SMILES OC(=O)[C@H]1C[C@H](N2Cc3ccccc3C2=O)c2c(Cl)cc(Cl)cc2N1
Show InChI InChI=1S/C18H14Cl2N2O3/c19-10-5-12(20)16-13(6-10)21-14(18(24)25)7-15(16)22-8-9-3-1-2-4-11(9)17(22)23/h1-6,14-15,21H,7-8H2,(H,24,25)/t14-,15+/m1/s1
PDB

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PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 27n/an/an/an/an/an/a



Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of [3H]- glycine binding to NMDA receptor from rat cortical membranes.

J Med Chem 35: 1954-68 (1992)


BindingDB Entry DOI: 10.7270/Q2T72GCZ
More data for this
Ligand-Target Pair