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Found 1 hit Enz. Inhib. hit(s) with Target = 'Glutamate receptor ionotropic, NMDA 1' and Ligand = 'BDBM50005051'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50005051
PNG
(5,7-Dimethyl-4-phenylacetylamino-1,2,3,4-tetrahydr...)
Show SMILES Cc1cc(C)c2[C@H](C[C@@H](Nc2c1)C(O)=O)NC(=O)Cc1ccccc1
Show InChI InChI=1S/C20H22N2O3/c1-12-8-13(2)19-15(9-12)21-17(20(24)25)11-16(19)22-18(23)10-14-6-4-3-5-7-14/h3-9,16-17,21H,10-11H2,1-2H3,(H,22,23)(H,24,25)/t16-,17+/m0/s1
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
PubMed
n/an/a 67n/an/an/an/an/an/a



Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of [3H]- glycine binding to NMDA receptor from rat cortical membranes.

J Med Chem 35: 1954-68 (1992)


BindingDB Entry DOI: 10.7270/Q2T72GCZ
More data for this
Ligand-Target Pair