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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Glutamate receptor ionotropic, NMDA 1' and Ligand = 'BDBM50252846'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50252846
PNG
((R)-1-(4-Methanesulfonamidophenoxy)-3-(N-(2-hydrox...)
Show SMILES CS(=O)(=O)Nc1ccc(OC[C@H](O)CN(CCO)CCc2ccc(Cl)c(Cl)c2)cc1 |r|
Show InChI InChI=1S/C20H26Cl2N2O5S/c1-30(27,28)23-16-3-5-18(6-4-16)29-14-17(26)13-24(10-11-25)9-8-15-2-7-19(21)20(22)12-15/h2-7,12,17,23,25-26H,8-11,13-14H2,1H3/t17-/m1/s1
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem

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Similars
Article
PubMed
n/an/a 173n/an/an/an/an/an/a



Emory University

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant NR1/NR2B receptor expressed in Xenopus oocytes assessed as inhibition of glutamate and glycine-induced evoked current b...

J Med Chem 51: 5506-21 (2008)


Article DOI: 10.1021/jm8002153
BindingDB Entry DOI: 10.7270/Q2PZ59QH
More data for this
Ligand-Target Pair