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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Glutamate receptor ionotropic, NMDA 1' and Ligand = 'BDBM50252849'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50252849
PNG
((R)-1-(4-Methanesulfonamidophenoxy)-3-(N-(3-hydrox...)
Show SMILES CS(=O)(=O)Nc1ccc(OC[C@H](O)CN(CCc2ccc(Cl)c(Cl)c2)Cc2cccc(O)c2)cc1 |r|
Show InChI InChI=1S/C25H28Cl2N2O5S/c1-35(32,33)28-20-6-8-23(9-7-20)34-17-22(31)16-29(15-19-3-2-4-21(30)13-19)12-11-18-5-10-24(26)25(27)14-18/h2-10,13-14,22,28,30-31H,11-12,15-17H2,1H3/t22-/m1/s1
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PC cid
PC sid
UniChem

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Similars
Article
PubMed
n/an/a 409n/an/an/an/an/an/a



Emory University

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant NR1/NR2B receptor expressed in Xenopus oocytes assessed as inhibition of glutamate and glycine-induced evoked current b...

J Med Chem 51: 5506-21 (2008)


Article DOI: 10.1021/jm8002153
BindingDB Entry DOI: 10.7270/Q2PZ59QH
More data for this
Ligand-Target Pair