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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Glutamate receptor ionotropic, NMDA 1' and Ligand = 'BDBM50253241'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glutamate receptor ionotropic, NMDA 1


(RAT)		BDBM50253241
PNG
((S)-1-(4-Methanesulfonamidophenoxy)-3-(N-(2,3,4-tr...)
Show SMILES CS(=O)(=O)Nc1ccc(OC[C@@H](O)CN(CCc2ccc(Cl)c(Cl)c2)Cc2ccc(F)c(F)c2F)cc1 |r|
Show InChI InChI=1S/C25H25Cl2F3N2O4S/c1-37(34,35)31-18-4-6-20(7-5-18)36-15-19(33)14-32(11-10-16-2-8-21(26)22(27)12-16)13-17-3-9-23(28)25(30)24(17)29/h2-9,12,19,31,33H,10-11,13-15H2,1H3/t19-/m0/s1
PDB

UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 51n/an/an/an/an/an/a



Emory University

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant NR1/NR2B receptor expressed in Xenopus oocytes assessed as inhibition of glutamate and glycine-induced evoked current b...

J Med Chem 51: 5506-21 (2008)


Article DOI: 10.1021/jm8002153
BindingDB Entry DOI: 10.7270/Q2PZ59QH
More data for this
Ligand-Target Pair