Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Glutamate receptor ionotropic, NMDA 2B' and Ligand = 'BDBM50269762'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor ionotropic, NMDA 2B (Rattus norvegicus (Rat))	BDBM50269762 (CHEMBL4063195) Show SMILES O[C@]1(Cc2noc(n2)-c2ccc(=O)[nH]c2)CC[C@H](Cc2ccc(Cl)cc2)CC1 |r,wD:1.0,17.19,(13.85,-7.13,;14.62,-8.46,;13.08,-8.46,;12.31,-9.8,;12.94,-11.2,;11.79,-12.23,;10.46,-11.46,;10.78,-9.95,;9.05,-12.09,;7.81,-11.18,;6.41,-11.8,;6.24,-13.33,;4.83,-13.95,;7.49,-14.24,;8.9,-13.62,;15.95,-7.68,;17.28,-8.46,;17.28,-10,;18.61,-10.77,;19.95,-10.01,;21.28,-10.78,;22.61,-10.01,;22.61,-8.47,;23.95,-7.7,;21.27,-7.7,;19.94,-8.47,;15.95,-10.76,;14.62,-10,)| Show InChI InChI=1S/C21H22ClN3O3/c22-17-4-1-14(2-5-17)11-15-7-9-21(27,10-8-15)12-18-24-20(28-25-18)16-3-6-19(26)23-13-16/h1-6,13,15,27H,7-12H2,(H,23,26)/t15-,21+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	126	n/a	n/a	n/a	n/a	n/a	n/a
Medicinal Chemistry Research Laboratory, Shionogi& Co Ltd, 1-1 Futabacho, 3-chome, Toyonaka 561-0825, Japan. Electronic address: kousuke.anan@shionogi.co.jp. Curated by ChEMBL					Assay Description Displacement of [3H]-ifenprodil from NR2B in Wistar rat brain membrane after 120 mins by liquid scintillation counting analysis				Bioorg Med Chem Lett 27: 4194-4198 (2017) Article DOI: 10.1016/j.bmcl.2017.06.076 BindingDB Entry DOI: 10.7270/Q2VX0K0Q
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B (Mus musculus)	BDBM50269762 (CHEMBL4063195) Show SMILES O[C@]1(Cc2noc(n2)-c2ccc(=O)[nH]c2)CC[C@H](Cc2ccc(Cl)cc2)CC1 |r,wD:1.0,17.19,(13.85,-7.13,;14.62,-8.46,;13.08,-8.46,;12.31,-9.8,;12.94,-11.2,;11.79,-12.23,;10.46,-11.46,;10.78,-9.95,;9.05,-12.09,;7.81,-11.18,;6.41,-11.8,;6.24,-13.33,;4.83,-13.95,;7.49,-14.24,;8.9,-13.62,;15.95,-7.68,;17.28,-8.46,;17.28,-10,;18.61,-10.77,;19.95,-10.01,;21.28,-10.78,;22.61,-10.01,;22.61,-8.47,;23.95,-7.7,;21.27,-7.7,;19.94,-8.47,;15.95,-10.76,;14.62,-10,)| Show InChI InChI=1S/C21H22ClN3O3/c22-17-4-1-14(2-5-17)11-15-7-9-21(27,10-8-15)12-18-24-20(28-25-18)16-3-6-19(26)23-13-16/h1-6,13,15,27H,7-12H2,(H,23,26)/t15-,21+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	158	n/a	n/a	n/a	n/a	n/a	n/a
Medicinal Chemistry Research Laboratory, Shionogi& Co Ltd, 1-1 Futabacho, 3-chome, Toyonaka 561-0825, Japan. Electronic address: kousuke.anan@shionogi.co.jp. Curated by ChEMBL					Assay Description Antagonist activity at mouse NR2B expressed in Hek293 cells co-expressing mouse NR1 assessed as inhibition of glutamic acid/glycine-induced intracell...				Bioorg Med Chem Lett 27: 4194-4198 (2017) Article DOI: 10.1016/j.bmcl.2017.06.076 BindingDB Entry DOI: 10.7270/Q2VX0K0Q
					More data for this Ligand-Target Pair