Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Glutamate receptor ionotropic, NMDA 2B' and Ligand = 'BDBM50398917'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor ionotropic, NMDA 2B (Rattus norvegicus (Rat))	BDBM50398917 (CHEMBL2178779) Show SMILES COc1ccc2CN(CCCC(=O)NC34CC5CC(C)(CC(C)(C5)C3)C4)CC[C@@]34C=C[C@H](O)C[C@@H]3Oc1c24 |r,c:32,TLB:19:18:15:23.24.21,22:21:15.14.25:17,13:14:23:20.18.17,13:14:23.21.20:17,25:14:23:20.18.17,THB:19:18:23:15.14.24,20:21:15:25.18.17,20:18:15:23.24.21,24:14:23.21.20:17,24:21:15.14.25:17,22:21:15:25.18.17,25:18:23:15.14.24| Show InChI InChI=1S/C32H44N2O4/c1-29-14-21-15-30(2,18-29)20-31(16-21,19-29)33-26(36)5-4-11-34-12-10-32-9-8-23(35)13-25(32)38-28-24(37-3)7-6-22(17-34)27(28)32/h6-9,21,23,25,35H,4-5,10-20H2,1-3H3,(H,33,36)/t21?,23-,25-,29?,30?,31?,32-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Istituto Italiano di Tecnologia Curated by ChEMBL					Assay Description Displacement of [3H]Ifenprodil from NMDAR-2B in Sprague-Dawley rat frontal cortex homogenates after 2 hrs by liquid scintillation counting				J Med Chem 55: 9708-21 (2012) Article DOI: 10.1021/jm3009458 BindingDB Entry DOI: 10.7270/Q2VQ33TR
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