Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Glutamate receptor ionotropic, NMDA 2C (Homo sapiens (Human)) | BDBM50503144 (CHEBI:35420 | CHEMBL1179605) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | 1.12E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bristol Curated by ChEMBL | Assay Description Negative allosteric modulation of GluN2C receptor (unknown origin) expressed in xenopus laevis oocytes assessed as reduction in glycine-induced chann... | J Med Chem 62: 3-23 (2019) Article DOI: 10.1021/acs.jmedchem.7b01640 BindingDB Entry DOI: 10.7270/Q2N019RG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, NMDA 2C (Homo sapiens (Human)) | BDBM50503144 (CHEBI:35420 | CHEMBL1179605) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | n/a | n/a | 8.30E+4 | n/a | n/a | n/a | n/a |
University of Bristol Curated by ChEMBL | Assay Description Positive allosteric modulation of EGFP-fused human GluN2C receptor expressed in HEK293T cells assessed as increase in glycine-induced channel current... | J Med Chem 62: 3-23 (2019) Article DOI: 10.1021/acs.jmedchem.7b01640 BindingDB Entry DOI: 10.7270/Q2N019RG | |||||||||||
More data for this Ligand-Target Pair |