Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Glutaminase kidney isoform, mitochondrial' and Ligand = 'BDBM405075'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM405075 (1-(2-fluoro-4-{4-[2-(pyridin-2- yl)acetamido]-1H-1...) Show SMILES FC(CCn1cc(NC(=O)Cc2ccccn2)nn1)Cn1cc(nn1)C(=O)NCc1cc(OC(F)(F)F)ccc1F Show InChI InChI=1S/C24H22F5N9O3/c25-16(6-8-37-14-21(34-36-37)32-22(39)10-17-3-1-2-7-30-17)12-38-13-20(33-35-38)23(40)31-11-15-9-18(4-5-19(15)26)41-24(27,28)29/h1-5,7,9,13-14,16H,6,8,10-12H2,(H,31,40)(H,32,39)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The inhibition of purified recombinant human GAC by varying concentrations of inhibitors is assessed via a dual-coupled enzymatic assay. The glutamat...				Citation and Details BindingDB Entry DOI: 10.7270/Q20Z76GP
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM405075 (1-(2-fluoro-4-{4-[2-(pyridin-2- yl)acetamido]-1H-1...) Show SMILES FC(CCn1cc(NC(=O)Cc2ccccn2)nn1)Cn1cc(nn1)C(=O)NCc1cc(OC(F)(F)F)ccc1F Show InChI InChI=1S/C24H22F5N9O3/c25-16(6-8-37-14-21(34-36-37)32-22(39)10-17-3-1-2-7-30-17)12-38-13-20(33-35-38)23(40)31-11-15-9-18(4-5-19(15)26)41-24(27,28)29/h1-5,7,9,13-14,16H,6,8,10-12H2,(H,31,40)(H,32,39)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
The University of Texas System US Patent					Assay Description The inhibition of purified recombinant human GAC by varying concentrations of inhibitors is assessed via a dual-coupled enzymatic assay. The glutamat...				US Patent US10344025 (2019) BindingDB Entry DOI: 10.7270/Q2765HQC
					More data for this Ligand-Target Pair