Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Glutaminase kidney isoform, mitochondrial' and Ligand = 'BDBM50509194'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM50509194 (CHEMBL4461569) Show SMILES Cc1ccc(Cn2cc(CCC(=O)Nc3ccc(CCCCc4nnc(NC(=O)Cc5ccccn5)s4)nn3)nn2)c(C)c1 Show InChI InChI=1S/C31H34N10O2S/c1-21-10-11-23(22(2)17-21)19-41-20-26(36-40-41)13-15-28(42)33-27-14-12-24(35-37-27)7-3-4-9-30-38-39-31(44-30)34-29(43)18-25-8-5-6-16-32-25/h5-6,8,10-12,14,16-17,20H,3-4,7,9,13,15,18-19H2,1-2H3,(H,33,37,42)(H,34,39,43)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of human GLS1 expressed in Escherichia coli strain BL21 (DE3)pLysS pre-incubated for 10 mins before glutamine addition and measured after ...				J Med Chem 62: 9642-9657 (2019) Article DOI: 10.1021/acs.jmedchem.9b01035 BindingDB Entry DOI: 10.7270/Q2057K75
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM50509194 (CHEMBL4461569) Show SMILES Cc1ccc(Cn2cc(CCC(=O)Nc3ccc(CCCCc4nnc(NC(=O)Cc5ccccn5)s4)nn3)nn2)c(C)c1 Show InChI InChI=1S/C31H34N10O2S/c1-21-10-11-23(22(2)17-21)19-41-20-26(36-40-41)13-15-28(42)33-27-14-12-24(35-37-27)7-3-4-9-30-38-39-31(44-30)34-29(43)18-25-8-5-6-16-32-25/h5-6,8,10-12,14,16-17,20H,3-4,7,9,13,15,18-19H2,1-2H3,(H,33,37,42)(H,34,39,43)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
China Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of N-[2-[(3',6'-dihydroxy-1-oxo-spiro[isobenzofuran-3,9'-xanthene]-5-yl)carbamothioylamino]ethyl]-N'-[6-[4-[5-[[2-(2-pyridyl)acetyl]amino]...				J Med Chem 62: 9642-9657 (2019) Article DOI: 10.1021/acs.jmedchem.9b01035 BindingDB Entry DOI: 10.7270/Q2057K75
					More data for this Ligand-Target Pair