Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Glutathione S-transferase P/Lysine-specific histone demethylase 1A [172-833]' and Ligand = 'BDBM256682'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutathione S-transferase P/Lysine-specific histone demethylase 1A [172-833] (Homo sapiens (Human))	BDBM256682 (US9487511, 61) Show SMILES Cn1ccc(NC(=O)c2cc(cs2)C2CC2NC2CCC2)c1 Show InChI InChI=1S/C17H21N3OS/c1-20-6-5-13(9-20)19-17(21)16-7-11(10-22-16)14-8-15(14)18-12-3-2-4-12/h5-7,9-10,12,14-15,18H,2-4,8H2,1H3,(H,19,21)	PDB UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	8.0	25
Takeda Pharmaceutical Company Limited US Patent					Assay Description A test compound dissolved in DMSO was added by to a reaction solution (50 mM Tris-HCl (pH 8.0), 0.1% BSA, 1 mM DTT) containing LSD1 enzyme, and the m...				US Patent US9487511 (2016) BindingDB Entry DOI: 10.7270/Q2V123Q4
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