Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Glutathione reductase, mitochondrial (Homo sapiens (Human)) | BDBM50177103 (1-(2'-chlorophenyl)penta-1,4-dien-3-one | CHEMBL22...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Biochemie-Zentrum der Universität Heidelberg Curated by ChEMBL | Assay Description Inhibition of human glutathione reductase after 5 mins preincubation with NADPH in presence of 500 uM GSSG substrate | J Med Chem 48: 7400-10 (2005) Article DOI: 10.1021/jm0504860 BindingDB Entry DOI: 10.7270/Q23X8662 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutathione reductase, mitochondrial (Homo sapiens (Human)) | BDBM50177103 (1-(2'-chlorophenyl)penta-1,4-dien-3-one | CHEMBL22...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.85E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Biochemie-Zentrum der Universität Heidelberg Curated by ChEMBL | Assay Description Inhibition of human glutathione reductase in presence of 50 uM GSSG substrate | J Med Chem 48: 7400-10 (2005) Article DOI: 10.1021/jm0504860 BindingDB Entry DOI: 10.7270/Q23X8662 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutathione reductase, mitochondrial (Homo sapiens (Human)) | BDBM50177103 (1-(2'-chlorophenyl)penta-1,4-dien-3-one | CHEMBL22...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.90E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Biochemie-Zentrum der Universität Heidelberg Curated by ChEMBL | Assay Description Inhibition of human glutathione reductase in presence of 500 uM GSSG substrate | J Med Chem 48: 7400-10 (2005) Article DOI: 10.1021/jm0504860 BindingDB Entry DOI: 10.7270/Q23X8662 | |||||||||||
More data for this Ligand-Target Pair |