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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Glycogen phosphorylase, liver form' and Ligand = 'BDBM50174396'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glycogen phosphorylase, liver form


(Homo sapiens (Human))
BDBM50174396
PNG
(4-[3-(2-Chloro-4,5-difluoro-benzoyl)-ureido]-3-(2,...)
Show SMILES OC(=O)c1ccc(NC(=O)NC(=O)c2cc(F)c(F)cc2Cl)c(OCC(F)(F)F)c1
Show InChI InChI=1S/C17H10ClF5N2O5/c18-9-5-11(20)10(19)4-8(9)14(26)25-16(29)24-12-2-1-7(15(27)28)3-13(12)30-6-17(21,22)23/h1-5H,6H2,(H,27,28)(H2,24,25,26,29)
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Article
PubMed
n/an/a 447n/an/an/an/a7.2n/a



Sanofi-Aventis Deutschland GmbH

Curated by ChEMBL


Assay Description
Logarithmic inhibitory concentration against human liver glycogen phosphorylase enzyme by the addition of glucose-1-phosphate and incubated for 40 mi...


J Med Chem 48: 6178-93 (2005)


Article DOI: 10.1021/jm049034y
BindingDB Entry DOI: 10.7270/Q2FT8KJ5
More data for this
Ligand-Target Pair
Glycogen phosphorylase, liver form


(Homo sapiens (Human))
BDBM50174396
PNG
(4-[3-(2-Chloro-4,5-difluoro-benzoyl)-ureido]-3-(2,...)
Show SMILES OC(=O)c1ccc(NC(=O)NC(=O)c2cc(F)c(F)cc2Cl)c(OCC(F)(F)F)c1
Show InChI InChI=1S/C17H10ClF5N2O5/c18-9-5-11(20)10(19)4-8(9)14(26)25-16(29)24-12-2-1-7(15(27)28)3-13(12)30-6-17(21,22)23/h1-5H,6H2,(H,27,28)(H2,24,25,26,29)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 450n/an/an/an/a7.2n/a



Sanofi-Aventis Deutschland GmbH

Curated by ChEMBL


Assay Description
Inhibitory concentration against human liver glycogen phosphorylase enzyme by the addition of glucose-1-phosphate upon incubating for 40 min at 25 de...


J Med Chem 48: 6178-93 (2005)


Article DOI: 10.1021/jm049034y
BindingDB Entry DOI: 10.7270/Q2FT8KJ5
More data for this
Ligand-Target Pair