Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Glycogen synthase kinase-3' and Ligand = 'BDBM50025653'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen synthase kinase-3 (Homo sapiens (Human))	BDBM50025653 (CHEMBL3335154) Show SMILES CO[C@H]1CC[C@@H](CC1)NC(=O)c1n[nH]cc1NC(=O)c1ncoc1-c1ccccc1 |r,wU:5.8,wD:2.1,(22.74,-5.31,;21.2,-5.3,;20.43,-6.63,;18.88,-6.62,;18.1,-7.95,;18.87,-9.28,;20.41,-9.29,;21.18,-7.97,;18.09,-10.61,;16.55,-10.6,;15.79,-9.27,;15.78,-11.93,;16.3,-13.39,;15.07,-14.32,;13.8,-13.45,;14.24,-11.98,;13.46,-10.66,;11.92,-10.67,;11.16,-12.01,;11.13,-9.35,;11.75,-7.93,;10.6,-6.91,;9.28,-7.7,;9.61,-9.2,;8.51,-10.3,;7.01,-9.9,;5.91,-10.99,;6.31,-12.5,;7.81,-12.9,;8.91,-11.8,)| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Inhibition of human GSK3 using biotinylated GSP2 substrate by flashplate assay				J Med Chem 57: 7536-49 (2014) Article DOI: 10.1021/jm500239b BindingDB Entry DOI: 10.7270/Q2M04712
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