Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Glycogen synthase kinase-3 beta' and Ligand = 'BDBM293466'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM293466 (US10106527, Compound 74 | US10544128, Compound 74 ...) Show SMILES CN1CCN(Cc2cccc(c2)C(=O)Nc2cc3cc(ccc3cn2)-c2cnn(C)c2)CC1 Show InChI InChI=1S/C26H28N6O/c1-30-8-10-32(11-9-30)17-19-4-3-5-21(12-19)26(33)29-25-14-23-13-20(6-7-22(23)15-27-25)24-16-28-31(2)18-24/h3-7,12-16,18H,8-11,17H2,1-2H3,(H,27,29,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	4.12E+3	n/a	n/a	n/a	25
Samumed, LLC US Patent					Assay Description Briefly, recombinant GSK3β kinase, ATP and Ser/Thr peptide 09 are prepared in 1× Kinase buffer to final concentrations of 0.04 μg/mL, 46 &#...				US Patent US10106527 (2018) BindingDB Entry DOI: 10.7270/Q2PN97Q3
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM293466 (US10106527, Compound 74 | US10544128, Compound 74 ...) Show SMILES CN1CCN(Cc2cccc(c2)C(=O)Nc2cc3cc(ccc3cn2)-c2cnn(C)c2)CC1 Show InChI InChI=1S/C26H28N6O/c1-30-8-10-32(11-9-30)17-19-4-3-5-21(12-19)26(33)29-25-14-23-13-20(6-7-22(23)15-27-25)24-16-28-31(2)18-24/h3-7,12-16,18H,8-11,17H2,1-2H3,(H,27,29,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	n/a	n/a	4.12E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2SJ1QR6
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM293466 (US10106527, Compound 74 | US10544128, Compound 74 ...) Show SMILES CN1CCN(Cc2cccc(c2)C(=O)Nc2cc3cc(ccc3cn2)-c2cnn(C)c2)CC1 Show InChI InChI=1S/C26H28N6O/c1-30-8-10-32(11-9-30)17-19-4-3-5-21(12-19)26(33)29-25-14-23-13-20(6-7-22(23)15-27-25)24-16-28-31(2)18-24/h3-7,12-16,18H,8-11,17H2,1-2H3,(H,27,29,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	4.12E+3	n/a	n/a	n/a	n/a
Samumed, LLC US Patent					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologies—a Di...				US Patent US10544128 (2020) BindingDB Entry DOI: 10.7270/Q2H134DS
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM293466 (US10106527, Compound 74 | US10544128, Compound 74 ...) Show SMILES CN1CCN(Cc2cccc(c2)C(=O)Nc2cc3cc(ccc3cn2)-c2cnn(C)c2)CC1 Show InChI InChI=1S/C26H28N6O/c1-30-8-10-32(11-9-30)17-19-4-3-5-21(12-19)26(33)29-25-14-23-13-20(6-7-22(23)15-27-25)24-16-28-31(2)18-24/h3-7,12-16,18H,8-11,17H2,1-2H3,(H,27,29,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	4.12E+3	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologiesa Div...				Bioorg Med Chem Lett 17: 4442-6 (2007) BindingDB Entry DOI: 10.7270/Q2862JRD
					More data for this Ligand-Target Pair