BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'Glycogen synthase kinase-3 beta' and Ligand = 'BDBM50129131'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50129131 (CHEBI:83275 \| Hypothemycin \| US10434085, Compound ...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE PC cid PC sid PDB UniChem Patents	Article PubMed	n/a	n/a	663	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human GSK-3beta preincubated for 3 hrs followed by ATP and substrate addition measured by serial dilution assay				Citation and Details Article DOI: 10.1016/j.bmc.2021.116179 BindingDB Entry DOI: 10.7270/Q2H70KMS
TBA					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50129131 (CHEBI:83275 \| Hypothemycin \| US10434085, Compound ...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE PC cid PC sid PDB UniChem Patents	Article PubMed	n/a	n/a	1.13E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human GSK-3beta incubated with substrate in presence of ATP measured by serial dilution assay				Citation and Details Article DOI: 10.1016/j.bmc.2021.116179 BindingDB Entry DOI: 10.7270/Q2H70KMS
TBA					More data for this Ligand-Target Pair