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Found 1 hit Enz. Inhib. hit(s) with Target = 'Glycogen synthase kinase-3 beta' and Ligand = 'BDBM50190185'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glycogen synthase kinase-3 beta


(Homo sapiens (Human))		BDBM50190185
PNG
(CHEMBL3827240)
Show SMILES CCOc1ccc(Nc2nnc(Cn3c(C)nc4ccccc34)s2)cc1
Show InChI InChI=1S/C19H19N5OS/c1-3-25-15-10-8-14(9-11-15)21-19-23-22-18(26-19)12-24-13(2)20-16-6-4-5-7-17(16)24/h4-11H,3,12H2,1-2H3,(H,21,23)
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Article
PubMed
n/an/a 293n/an/an/an/an/an/a



Jamia Hamdard (Hamdard University)

Curated by ChEMBL


Assay Description
Inhibition of recombinant human N-terminal His-tagged GSK-3beta expressed in Escherichia coli using glycogen synthase-2 as substrate and ATP measured...

Bioorg Med Chem Lett 26: 4020-4 (2016)


Article DOI: 10.1016/j.bmcl.2016.06.084
BindingDB Entry DOI: 10.7270/Q2639RP0
More data for this
Ligand-Target Pair