Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Glycogen synthase kinase-3 beta' and Ligand = 'BDBM7375'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen synthase kinase-3 beta (Rattus norvegicus (rat))	BDBM7375 (4-{7-methyl-5H-pyrrolo[2,3-b]pyrazin-6-yl}phenol |...) Show SMILES Cc1c([nH]c2nccnc12)-c1ccc(O)cc1 Show InChI InChI=1S/C13H11N3O/c1-8-11(9-2-4-10(17)5-3-9)16-13-12(8)14-6-7-15-13/h2-7,17H,1H3,(H,15,16)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	520	n/a	n/a	n/a	n/a	n/a	30
Faculte de Medecine et de Pharmacie					Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...				J Med Chem 46: 222-36 (2003) Article DOI: 10.1021/jm020319p BindingDB Entry DOI: 10.7270/Q2474820
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