Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Glycogen synthase kinase-3 beta' and Ligand = 'BDBM8565'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM8565 (4-Acylamino-6-arylfuro[2,3-d]pyrimidine 10 | N-[6-...) Show SMILES COc1ccc(cc1)-c1cc2c(NC(=O)C3CCCCC3)ncnc2o1 Show InChI InChI=1S/C20H21N3O3/c1-25-15-9-7-13(8-10-15)17-11-16-18(21-12-22-20(16)26-17)23-19(24)14-5-3-2-4-6-14/h7-12,14H,2-6H2,1H3,(H,21,22,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.82E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wuhan Institute of Technology Curated by ChEMBL					Assay Description Inhibition of human Protein kinase C alpha				Eur J Med Chem 164: 448-470 (2019) Article DOI: 10.1016/j.ejmech.2018.12.073 BindingDB Entry DOI: 10.7270/Q2WH2SVB
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM8565 (4-Acylamino-6-arylfuro[2,3-d]pyrimidine 10 | N-[6-...) Show SMILES COc1ccc(cc1)-c1cc2c(NC(=O)C3CCCCC3)ncnc2o1 Show InChI InChI=1S/C20H21N3O3/c1-25-15-9-7-13(8-10-15)17-11-16-18(21-12-22-20(16)26-17)23-19(24)14-5-3-2-4-6-14/h7-12,14H,2-6H2,1H3,(H,21,22,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.82E+3	n/a	n/a	n/a	n/a	7.2	22
Tsukuba Research Laboratories					Assay Description The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 2.5 uM ATP/ [gamma-32P] ATP. Af...				Bioorg Med Chem Lett 14: 3907-11 (2004) Article DOI: 10.1016/j.bmcl.2004.05.064 BindingDB Entry DOI: 10.7270/Q2XD0ZWC
					More data for this Ligand-Target Pair