Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Gonadotropin-releasing hormone receptor' and Ligand = 'BDBM50101201'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50101201 (CHEMBL50380 | {2-(3,5-Dimethyl-phenyl)-3-[2-(4-pyr...) Show SMILES CC1CCC(C)N1C(=O)c1ccc2[nH]c(c(CCNCCCCc3cccnc3)c2c1)-c1cc(C)cc(C)c1 Show InChI InChI=1S/C34H42N4O/c1-23-18-24(2)20-29(19-23)33-30(14-17-35-15-6-5-8-27-9-7-16-36-22-27)31-21-28(12-13-32(31)37-33)34(39)38-25(3)10-11-26(38)4/h7,9,12-13,16,18-22,25-26,35,37H,5-6,8,10-11,14-15,17H2,1-4H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.60	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [125I]-buserelin binding to rat Gonadotropin-releasing hormone receptor.				Bioorg Med Chem Lett 11: 1727-31 (2001) BindingDB Entry DOI: 10.7270/Q2FQ9VW9
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50101201 (CHEMBL50380 | {2-(3,5-Dimethyl-phenyl)-3-[2-(4-pyr...) Show SMILES CC1CCC(C)N1C(=O)c1ccc2[nH]c(c(CCNCCCCc3cccnc3)c2c1)-c1cc(C)cc(C)c1 Show InChI InChI=1S/C34H42N4O/c1-23-18-24(2)20-29(19-23)33-30(14-17-35-15-6-5-8-27-9-7-16-36-22-27)31-21-28(12-13-32(31)37-33)34(39)38-25(3)10-11-26(38)4/h7,9,12-13,16,18-22,25-26,35,37H,5-6,8,10-11,14-15,17H2,1-4H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	62	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of GnRH-stimulated phosphatidyinositol (PI) hydrolysis in cloned chinese hamster ovary (CHO) cells expressing human GnRH receptor.				Bioorg Med Chem Lett 11: 1727-31 (2001) BindingDB Entry DOI: 10.7270/Q2FQ9VW9
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Rattus norvegicus)	BDBM50101201 (CHEMBL50380 | {2-(3,5-Dimethyl-phenyl)-3-[2-(4-pyr...) Show SMILES CC1CCC(C)N1C(=O)c1ccc2[nH]c(c(CCNCCCCc3cccnc3)c2c1)-c1cc(C)cc(C)c1 Show InChI InChI=1S/C34H42N4O/c1-23-18-24(2)20-29(19-23)33-30(14-17-35-15-6-5-8-27-9-7-16-36-22-27)31-21-28(12-13-32(31)37-33)34(39)38-25(3)10-11-26(38)4/h7,9,12-13,16,18-22,25-26,35,37H,5-6,8,10-11,14-15,17H2,1-4H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	360	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of GnRH-stimulated luteinizing hormone (LH) release in rat pituitary cells				Bioorg Med Chem Lett 11: 1727-31 (2001) BindingDB Entry DOI: 10.7270/Q2FQ9VW9
					More data for this Ligand-Target Pair