Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Gonadotropin-releasing hormone receptor' and Ligand = 'BDBM50101224'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gonadotropin-releasing hormone receptor (Rattus norvegicus)	BDBM50101224 (2-{2-(3,5-Dimethyl-phenyl)-3-[2-(4-pyridin-4-yl-bu...) Show SMILES Cc1cc(C)cc(c1)-c1[nH]c2ccc(cc2c1CCNCCCCc1ccncc1)C(C)(C)C(=O)N1CCCCC1 Show InChI InChI=1S/C36H46N4O/c1-26-22-27(2)24-29(23-26)34-31(15-19-37-16-7-6-10-28-13-17-38-18-14-28)32-25-30(11-12-33(32)39-34)36(3,4)35(41)40-20-8-5-9-21-40/h11-14,17-18,22-25,37,39H,5-10,15-16,19-21H2,1-4H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [125I]-buserelin binding to rat Gonadotropin-releasing hormone receptor.				Bioorg Med Chem Lett 11: 1727-31 (2001) BindingDB Entry DOI: 10.7270/Q2FQ9VW9
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50101224 (2-{2-(3,5-Dimethyl-phenyl)-3-[2-(4-pyridin-4-yl-bu...) Show SMILES Cc1cc(C)cc(c1)-c1[nH]c2ccc(cc2c1CCNCCCCc1ccncc1)C(C)(C)C(=O)N1CCCCC1 Show InChI InChI=1S/C36H46N4O/c1-26-22-27(2)24-29(23-26)34-31(15-19-37-16-7-6-10-28-13-17-38-18-14-28)32-25-30(11-12-33(32)39-34)36(3,4)35(41)40-20-8-5-9-21-40/h11-14,17-18,22-25,37,39H,5-10,15-16,19-21H2,1-4H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of GnRH-stimulated phosphatidyinositol (PI) hydrolysis in cloned chinese hamster ovary (CHO) cells expressing human GnRH receptor.				Bioorg Med Chem Lett 11: 1727-31 (2001) BindingDB Entry DOI: 10.7270/Q2FQ9VW9
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Rattus norvegicus)	BDBM50101224 (2-{2-(3,5-Dimethyl-phenyl)-3-[2-(4-pyridin-4-yl-bu...) Show SMILES Cc1cc(C)cc(c1)-c1[nH]c2ccc(cc2c1CCNCCCCc1ccncc1)C(C)(C)C(=O)N1CCCCC1 Show InChI InChI=1S/C36H46N4O/c1-26-22-27(2)24-29(23-26)34-31(15-19-37-16-7-6-10-28-13-17-38-18-14-28)32-25-30(11-12-33(32)39-34)36(3,4)35(41)40-20-8-5-9-21-40/h11-14,17-18,22-25,37,39H,5-10,15-16,19-21H2,1-4H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [125I]-buserelin binding to rat Gonadotropin-releasing hormone receptor.				Bioorg Med Chem Lett 11: 1727-31 (2001) BindingDB Entry DOI: 10.7270/Q2FQ9VW9
					More data for this Ligand-Target Pair