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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Gonadotropin-releasing hormone receptor' and Ligand = 'BDBM50109236'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Gonadotropin-releasing hormone receptor


(Homo sapiens (Human))		BDBM50109236
PNG
(7-(4-Butyrylamino-phenyl)-1-(2-fluoro-benzyl)-6-{[...)
Show SMILES CCCC(=O)Nc1ccc(cc1)-c1cc2n(Cc3ccccc3F)cc(C(=O)NCCOC)c(=O)n2c1CN(C)CCc1ccccn1
Show InChI InChI=1S/C37H41FN6O4/c1-4-9-34(45)41-29-15-13-26(14-16-29)30-22-35-43(23-27-10-5-6-12-32(27)38)24-31(36(46)40-19-21-48-3)37(47)44(35)33(30)25-42(2)20-17-28-11-7-8-18-39-28/h5-8,10-16,18,22,24H,4,9,17,19-21,23,25H2,1-3H3,(H,40,46)(H,41,45)
PDB

KEGG

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PC cid
PC sid
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Similars
PubMed
 630n/an/an/an/an/an/an/an/a



Neurocrine Biosciences, Inc.

Curated by ChEMBL


Assay Description
Binding affinity to human gonadotropin-releasing hormone (hGnRH) receptor expressed in HEK293 cells using des-Gly10[125I-Tyr,5DLeu,6NMeLeu,7Pro9-NEt]...

Bioorg Med Chem Lett 12: 403-6 (2002)


BindingDB Entry DOI: 10.7270/Q2542MXV
More data for this
Ligand-Target Pair