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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Gonadotropin-releasing hormone receptor' and Ligand = 'BDBM50109241'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Gonadotropin-releasing hormone receptor


(Homo sapiens (Human))		BDBM50109241
PNG
(7-(4-Amino-phenyl)-6-[(benzyl-methyl-amino)-methyl...)
Show SMILES CCOC(=O)c1cn(Cc2ccccc2F)c2cc(c(CN(C)Cc3ccccc3)n2c1=O)-c1ccc(N)cc1
Show InChI InChI=1S/C32H31FN4O3/c1-3-40-32(39)27-20-36(19-24-11-7-8-12-28(24)33)30-17-26(23-13-15-25(34)16-14-23)29(37(30)31(27)38)21-35(2)18-22-9-5-4-6-10-22/h4-17,20H,3,18-19,21,34H2,1-2H3
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PC cid
PC sid
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Similars
PubMed
 190n/an/an/an/an/an/an/an/a



Neurocrine Biosciences, Inc.

Curated by ChEMBL


Assay Description
Binding affinity to human gonadotropin-releasing hormone (hGnRH) receptor expressed in HEK293 cells using des-Gly10[125I-Tyr,5DLeu,6NMeLeu,7Pro9-NEt]...

Bioorg Med Chem Lett 12: 403-6 (2002)


BindingDB Entry DOI: 10.7270/Q2542MXV
More data for this
Ligand-Target Pair