Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Gonadotropin-releasing hormone receptor' and Ligand = 'BDBM50162037'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50162037 (1-(2,6-Difluoro-benzyl)-3-((S)-2-dimethylamino-4-m...) Show SMILES COc1cccc(c1F)-c1c(C)n(Cc2c(F)cccc2F)c(=O)n(C[C@H](CC(C)C)N(C)C)c1=O |wU:26.32,(2.43,6.15,;3.76,5.38,;3.76,3.85,;5.11,3.07,;5.11,1.53,;3.76,.76,;2.43,1.54,;2.43,3.07,;1.1,3.85,;1.1,.77,;1.1,-.77,;2.43,-1.54,;-.23,-1.52,;-.23,-3.06,;1.1,-3.83,;2.43,-3.06,;1.08,-2.29,;3.76,-3.83,;3.76,-5.37,;2.43,-6.14,;1.1,-5.37,;-.25,-6.14,;-1.56,-.77,;-2.89,-1.54,;-1.56,.77,;-2.89,1.54,;-4.22,.76,;-5.57,1.53,;-5.57,3.07,;-6.9,3.85,;-4.22,3.85,;-4.22,-.78,;-5.55,-1.55,;-4.22,-2.31,;-.23,1.56,;-.23,3.1,)| Show InChI InChI=1S/C27H32F3N3O3/c1-16(2)13-18(31(4)5)14-33-26(34)24(19-9-7-12-23(36-6)25(19)30)17(3)32(27(33)35)15-20-21(28)10-8-11-22(20)29/h7-12,16,18H,13-15H2,1-6H3/t18-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity for Human gonadotropin-releasing hormone receptor				J Med Chem 48: 1169-78 (2005) Article DOI: 10.1021/jm049218c BindingDB Entry DOI: 10.7270/Q2MK6CD8
					More data for this Ligand-Target Pair