Compile Data Set for Download or QSAR

Found 6 hits Enz. Inhib. hit(s) with Target = 'Gonadotropin-releasing hormone receptor' and Ligand = 'BDBM50548472'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50548472 (CHEMBL4749790) Show SMILES COc1ccc(cc1)S(=O)(=O)N1C(C)C2(CCN(CC2)C(C)=O)c2cc(ccc12)C(=O)NCc1ccccc1Cl Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at human GnRH receptor expressed in CHO-K1 cells assessed as inhibition of LHRH-induced response preincubated for 20 mins followe...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01076 BindingDB Entry DOI: 10.7270/Q26D5XK9
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50548472 (CHEMBL4749790) Show SMILES COc1ccc(cc1)S(=O)(=O)N1C(C)C2(CCN(CC2)C(C)=O)c2cc(ccc12)C(=O)NCc1ccccc1Cl Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at human GnRH receptor expressed in CHO-K1 cells assessed as inhibition of LHRH-induced response preincubated for 20 mins followe...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01076 BindingDB Entry DOI: 10.7270/Q26D5XK9
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50548472 (CHEMBL4749790) Show SMILES COc1ccc(cc1)S(=O)(=O)N1C(C)C2(CCN(CC2)C(C)=O)c2cc(ccc12)C(=O)NCc1ccccc1Cl Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at human GnRH receptor expressed in CHO-K1 cells assessed as inhibition of buserelin-induced response preincubated for 20 mins fo...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01076 BindingDB Entry DOI: 10.7270/Q26D5XK9
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Homo sapiens (Human))	BDBM50548472 (CHEMBL4749790) Show SMILES COc1ccc(cc1)S(=O)(=O)N1C(C)C2(CCN(CC2)C(C)=O)c2cc(ccc12)C(=O)NCc1ccccc1Cl Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at human GnRH receptor expressed in CHO-K1 cells assessed as inhibition of buserelin-induced response preincubated for 20 mins fo...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01076 BindingDB Entry DOI: 10.7270/Q26D5XK9
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Rattus norvegicus)	BDBM50548472 (CHEMBL4749790) Show SMILES COc1ccc(cc1)S(=O)(=O)N1C(C)C2(CCN(CC2)C(C)=O)c2cc(ccc12)C(=O)NCc1ccccc1Cl Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at rat GnRH receptor expressed in CHO-K1 cells assessed as inhibition of LHRH-induced response preincubated for 20 mins followed ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01076 BindingDB Entry DOI: 10.7270/Q26D5XK9
					More data for this Ligand-Target Pair
Gonadotropin-releasing hormone receptor (Rattus norvegicus)	BDBM50548472 (CHEMBL4749790) Show SMILES COc1ccc(cc1)S(=O)(=O)N1C(C)C2(CCN(CC2)C(C)=O)c2cc(ccc12)C(=O)NCc1ccccc1Cl Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at rat GnRH receptor expressed in CHO-K1 cells assessed as inhibition of buserelin-induced response preincubated for 20 mins foll...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01076 BindingDB Entry DOI: 10.7270/Q26D5XK9
					More data for this Ligand-Target Pair