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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Group 10 secretory phospholipase A2' and Ligand = 'BDBM50366968'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Group 10 secretory phospholipase A2


(Homo sapiens (Human))		BDBM50366968
PNG
(CHEMBL4161605)
Show SMILES NC(=O)c1cc2ccc(F)cc2n1-c1cccc(CCC(O)=O)c1
Show InChI InChI=1S/C18H15FN2O3/c19-13-6-5-12-9-16(18(20)24)21(15(12)10-13)14-3-1-2-11(8-14)4-7-17(22)23/h1-3,5-6,8-10H,4,7H2,(H2,20,24)(H,22,23)
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Similars
Article
PubMed
n/an/a 260n/an/an/an/an/an/a



AstraZeneca

Curated by ChEMBL


Assay Description
Inhibition of recombinant human sPLA2-10 expressed in Escherichia coli BL21(DE3) using 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine as substrate ...

ACS Med Chem Lett 9: 594-599 (2018)


Article DOI: 10.1021/acsmedchemlett.7b00505
BindingDB Entry DOI: 10.7270/Q2Z60RMJ
More data for this
Ligand-Target Pair