Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Growth hormone secretagogue receptor type 1' and Ligand = 'BDBM50165602'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Growth hormone secretagogue receptor type 1 (Homo sapiens (Human))	BDBM50165602 (CHEMBL3799604) Show SMILES COc1ccc(Cn2c(nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)c2ccccn2)[C@H](Cc2c[nH]c3ccccc23)NC=O)cc1 |r| Show InChI InChI=1S/C37H34N8O3/c1-48-27-15-13-24(14-16-27)22-45-35(33(41-23-46)18-25-20-39-30-10-4-2-8-28(25)30)43-44-36(45)34(42-37(47)32-12-6-7-17-38-32)19-26-21-40-31-11-5-3-9-29(26)31/h2-17,20-21,23,33-34,39-40H,18-19,22H2,1H3,(H,41,46)(H,42,47)/t33-,34+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	154	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Montpellier Curated by ChEMBL					Assay Description Displacement of [125I]-His9-ghrelin from human GHS-R1a transfected in pig LLC PK-1 cell membranes after 60 mins by gamma counting method				Bioorg Med Chem Lett 26: 2408-12 (2016) Article DOI: 10.1016/j.bmcl.2016.04.003 BindingDB Entry DOI: 10.7270/Q2J9688V
					More data for this Ligand-Target Pair
Growth hormone secretagogue receptor type 1 (Homo sapiens (Human))	BDBM50165602 (CHEMBL3799604) Show SMILES COc1ccc(Cn2c(nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)c2ccccn2)[C@H](Cc2c[nH]c3ccccc23)NC=O)cc1 |r| Show InChI InChI=1S/C37H34N8O3/c1-48-27-15-13-24(14-16-27)22-45-35(33(41-23-46)18-25-20-39-30-10-4-2-8-28(25)30)43-44-36(45)34(42-37(47)32-12-6-7-17-38-32)19-26-21-40-31-11-5-3-9-29(26)31/h2-17,20-21,23,33-34,39-40H,18-19,22H2,1H3,(H,41,46)(H,42,47)/t33-,34+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	410	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Montpellier Curated by ChEMBL					Assay Description Antagonist activity at human GHS-R1a transfected in mouse LTK cells after 6 hrs by CRE/luciferase reporter gene assay in presence of ghrelin and roli...				Bioorg Med Chem Lett 26: 2408-12 (2016) Article DOI: 10.1016/j.bmcl.2016.04.003 BindingDB Entry DOI: 10.7270/Q2J9688V
					More data for this Ligand-Target Pair
Growth hormone secretagogue receptor type 1 (Homo sapiens (Human))	BDBM50165602 (CHEMBL3799604) Show SMILES COc1ccc(Cn2c(nnc2[C@@H](Cc2c[nH]c3ccccc23)NC(=O)c2ccccn2)[C@H](Cc2c[nH]c3ccccc23)NC=O)cc1 |r| Show InChI InChI=1S/C37H34N8O3/c1-48-27-15-13-24(14-16-27)22-45-35(33(41-23-46)18-25-20-39-30-10-4-2-8-28(25)30)43-44-36(45)34(42-37(47)32-12-6-7-17-38-32)19-26-21-40-31-11-5-3-9-29(26)31/h2-17,20-21,23,33-34,39-40H,18-19,22H2,1H3,(H,41,46)(H,42,47)/t33-,34+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Montpellier Curated by ChEMBL					Assay Description Antagonist activity at human GHS-R1a transfected in CHO cells assessed as inhibition of ghrelin-induced intracellular calcium mobilization measured o...				Bioorg Med Chem Lett 26: 2408-12 (2016) Article DOI: 10.1016/j.bmcl.2016.04.003 BindingDB Entry DOI: 10.7270/Q2J9688V
					More data for this Ligand-Target Pair