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Found 1 hit Enz. Inhib. hit(s) with Target = 'Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2' and Ligand = 'BDBM50514450'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2


(Homo sapiens)		BDBM50514450
PNG
(CHEMBL4443974)
Show SMILES OC(=O)C1CC23C(Cl)C(Cl)=C(Cl)C(Cl)C2(CC1c1c2ccc(O)c(O)c2oc2c(O)c(=O)ccc12)C3(Cl)Cl |t:9|
Show InChI InChI=1S/C25H16Cl6O7/c26-14-15(27)21(29)24-6-10(22(36)37)9(5-23(24,20(14)28)25(24,30)31)13-7-1-3-11(32)16(34)18(7)38-19-8(13)2-4-12(33)17(19)35/h1-4,9-10,20-21,32,34-35H,5-6H2,(H,36,37)
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 250n/an/an/an/an/an/a



Sun Yat-sen University

Curated by ChEMBL


Assay Description
Inhibition of G-protein beta1gamma2 (unknown origin) by flow cytometry

J Med Chem 63: 5013-5030 (2020)


Article DOI: 10.1021/acs.jmedchem.9b01452
BindingDB Entry DOI: 10.7270/Q28S4T82
More data for this
Ligand-Target Pair