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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Guanine nucleotide-binding protein G(o) subunit alpha' and Ligand = 'BDBM50468903'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Guanine nucleotide-binding protein G(o) subunit alpha


(Rattus norvegicus)		BDBM50468903
PNG
(CHEMBL4279374)
Show SMILES CO[C@H](C)[C@@H]1N(C)C(=O)[C@@H](NC(=O)[C@H](C)N(C)C(=O)[C@H](C)NC(=O)[C@@H](CO)N(C)C(=O)[C@@H](CC(C)C)OC(=O)[C@@H](NC(C)=O)[C@@H](C)OC1=O)[C@H](OC(=O)[C@@H](NC(C)=O)[C@H](O)C(C)C)C(C)C |r|
Show InChI InChI=1S/C43H73N7O16/c1-19(2)17-29-39(58)49(14)28(18-51)37(56)44-22(7)38(57)48(13)23(8)36(55)47-32(35(21(5)6)66-42(61)31(46-27(12)53)34(54)20(3)4)40(59)50(15)33(25(10)63-16)43(62)64-24(9)30(41(60)65-29)45-26(11)52/h19-25,28-35,51,54H,17-18H2,1-16H3,(H,44,56)(H,45,52)(H,46,53)(H,47,55)/t22-,23-,24+,25+,28+,29+,30-,31-,32-,33-,34+,35+/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



University of Copenhagen

Curated by ChEMBL


Assay Description
Inhibition of recombinant rat Gi coupled mGlu2 receptor expressed in CHO cells assessed as suppression of L-glutamate-induced decrease in cAMP level ...

Eur J Med Chem 156: 847-860 (2018)


Article DOI: 10.1016/j.ejmech.2018.07.023
BindingDB Entry DOI: 10.7270/Q2BP05GZ
More data for this
Ligand-Target Pair