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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Guanine nucleotide-binding protein G(o) subunit alpha' and Ligand = 'BDBM50468904'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Guanine nucleotide-binding protein G(o) subunit alpha


(Rattus norvegicus)		BDBM50468904
PNG
(CHEMBL4173778)
Show SMILES CO[C@H](C)[C@@H]1N(C)C(=O)[C@@H](NC(=O)[C@H](C)N(C)C(=O)[C@H](C)NC(=O)C(=C)N(C)C(=O)[C@@H](Cc2ccccc2)OC(=O)[C@@H](NC(C)=O)[C@H](OC1=O)C(C)C)[C@H](OC(=O)[C@@H](NC(C)=O)[C@H](O)C(C)C)C(C)C |r|
Show InChI InChI=1S/C48H73N7O15/c1-23(2)38(58)34(50-30(11)56)46(64)69-39(24(3)4)35-45(63)55(15)37(29(10)67-16)48(66)70-40(25(5)6)36(51-31(12)57)47(65)68-33(22-32-20-18-17-19-21-32)44(62)54(14)27(8)41(59)49-26(7)43(61)53(13)28(9)42(60)52-35/h17-21,23-26,28-29,33-40,58H,8,22H2,1-7,9-16H3,(H,49,59)(H,50,56)(H,51,57)(H,52,60)/t26-,28-,29+,33+,34-,35-,36-,37-,38+,39+,40+/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>5.00E+4n/an/an/an/an/an/a



University of Copenhagen

Curated by ChEMBL


Assay Description
Inhibition of recombinant rat Gi coupled mGlu2 receptor expressed in CHO cells assessed as suppression of L-glutamate-induced decrease in cAMP level ...

Eur J Med Chem 156: 847-860 (2018)


Article DOI: 10.1016/j.ejmech.2018.07.023
BindingDB Entry DOI: 10.7270/Q2BP05GZ
More data for this
Ligand-Target Pair