Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Guanylate cyclase soluble subunit alpha-1/beta-1' and Ligand = 'BDBM430649'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Guanylate cyclase soluble subunit alpha-1/beta-1 (Homo sapiens (Human))	BDBM430649 (US10550102, Example (+)-1. b)) Show SMILES Cc1cc(ccc1OC1CCc2cccc(c12)-c1cccc(c1)-n1ncc(C(O)=O)c1C(F)(F)F)C1CCN(CC1)C(=O)C1CC1 Show InChI InChI=1S/C36H34F3N3O4/c1-21-18-25(22-14-16-41(17-15-22)34(43)24-8-9-24)11-12-30(21)46-31-13-10-23-4-3-7-28(32(23)31)26-5-2-6-27(19-26)42-33(36(37,38)39)29(20-40-42)35(44)45/h2-7,11-12,18-20,22,24,31H,8-10,13-17H2,1H3,(H,44,45)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.5	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent					Assay Description Chinese hamster ovary (CHO) cells overexpressing soluble guanylate cyclase were generated to test the effect of sGC activators in a cellular context....				US Patent US10550102 (2020) BindingDB Entry DOI: 10.7270/Q2PC34SQ
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