Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Guanylate cyclase soluble subunit alpha-1/beta-1' and Ligand = 'BDBM430678'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Guanylate cyclase soluble subunit alpha-1/beta-1 (Homo sapiens (Human))	BDBM430678 (Example 2-A. (+)-(S)-Ethyl-1-(3-(3-(4-(1-(cyclopro...) Show SMILES Cc1c(cnn1-c1cccc(c1)-c1cccc2CC[C@H](Oc3ccc(cc3C)C3CCN(CC3)C(=O)C3CC3)c12)C(O)=O |r| Show InChI InChI=1S/C36H37N3O4/c1-22-19-27(24-15-17-38(18-16-24)35(40)26-9-10-26)12-13-32(22)43-33-14-11-25-5-4-8-30(34(25)33)28-6-3-7-29(20-28)39-23(2)31(21-37-39)36(41)42/h3-8,12-13,19-21,24,26,33H,9-11,14-18H2,1-2H3,(H,41,42)/t33-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	1	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent					Assay Description Chinese hamster ovary (CHO) cells overexpressing soluble guanylate cyclase were generated to test the effect of sGC activators in a cellular context....				US Patent US10550102 (2020) BindingDB Entry DOI: 10.7270/Q2PC34SQ
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