Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Guanylate cyclase soluble subunit alpha-1/beta-1' and Ligand = 'BDBM430985'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Guanylate cyclase soluble subunit alpha-1/beta-1 (Homo sapiens (Human))	BDBM430985 (Example 60-A. (+-)-Ethyl 1-(6-(3-((4-(1-cyclopropy...) Show SMILES Cc1c(cnn1-c1cccc(n1)-c1cccc2CCC(Nc3ccc(cc3C)C3CCN(CC3)C3CC3)c12)C(O)=O Show InChI InChI=1S/C34H37N5O2/c1-21-19-25(23-15-17-38(18-16-23)26-11-12-26)10-13-29(21)36-31-14-9-24-5-3-6-27(33(24)31)30-7-4-8-32(37-30)39-22(2)28(20-35-39)34(40)41/h3-8,10,13,19-20,23,26,31,36H,9,11-12,14-18H2,1-2H3,(H,40,41)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	5.30	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent					Assay Description Chinese hamster ovary (CHO) cells overexpressing soluble guanylate cyclase were generated to test the effect of sGC activators in a cellular context....				US Patent US10550102 (2020) BindingDB Entry DOI: 10.7270/Q2PC34SQ
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