Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Guanylate cyclase soluble subunit alpha-1/beta-1' and Ligand = 'BDBM430988'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Guanylate cyclase soluble subunit alpha-1/beta-1 (Homo sapiens (Human))	BDBM430988 (US10550102, Example 40-2 (-)) Show SMILES CCc1c(cnn1-c1cccc(n1)-c1cccc2CCC(Cc3ccc(cc3C)C3CCN(CC3)C(=O)[C@H](C)O)c12)C(O)=O |r| Show InChI InChI=1S/C36H40N4O4/c1-4-32-30(36(43)44)21-37-40(32)33-10-6-9-31(38-33)29-8-5-7-25-11-14-28(34(25)29)20-26-12-13-27(19-22(26)2)24-15-17-39(18-16-24)35(42)23(3)41/h5-10,12-13,19,21,23-24,28,41H,4,11,14-18,20H2,1-3H3,(H,43,44)/t23-,28?/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	25	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent					Assay Description Chinese hamster ovary (CHO) cells overexpressing soluble guanylate cyclase were generated to test the effect of sGC activators in a cellular context....				US Patent US10550102 (2020) BindingDB Entry DOI: 10.7270/Q2PC34SQ
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