Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Guanylate cyclase soluble subunit alpha-1/beta-1' and Ligand = 'BDBM430991'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Guanylate cyclase soluble subunit alpha-1/beta-1 (Homo sapiens (Human))	BDBM430991 (Example 62-A. (+-)-Ethyl 1-(6-(3-((tert-butoxycarb...) Show SMILES Cc1c(cnn1-c1cccc(n1)-c1cccc2CCC(Nc3ncc(cc3C)C3CCN(CC3)C(=O)C3CC3)c12)C(O)=O Show InChI InChI=1S/C34H36N6O3/c1-20-17-25(22-13-15-39(16-14-22)33(41)24-9-10-24)18-35-32(20)38-29-12-11-23-5-3-6-26(31(23)29)28-7-4-8-30(37-28)40-21(2)27(19-36-40)34(42)43/h3-8,17-19,22,24,29H,9-16H2,1-2H3,(H,35,38)(H,42,43)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	6	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent					Assay Description Chinese hamster ovary (CHO) cells overexpressing soluble guanylate cyclase were generated to test the effect of sGC activators in a cellular context....				US Patent US10550102 (2020) BindingDB Entry DOI: 10.7270/Q2PC34SQ
					More data for this Ligand-Target Pair