Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Guanylate cyclase soluble subunit alpha-1/beta-1' and Ligand = 'BDBM430995'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Guanylate cyclase soluble subunit alpha-1/beta-1 (Homo sapiens (Human))	BDBM430995 (US10550102, Example 63b) Show SMILES CCOC(=O)c1cnn(c1CC)-c1cccc(n1)-c1cccc2CCC(Nc3ccc(C4CCN(CC4)C(=O)C4CC4)c(CC)n3)c12 Show InChI InChI=1S/C38H44N6O3/c1-4-30-27(24-19-21-43(22-20-24)37(45)26-13-14-26)16-18-34(40-30)41-32-17-15-25-9-7-10-28(36(25)32)31-11-8-12-35(42-31)44-33(5-2)29(23-39-44)38(46)47-6-3/h7-12,16,18,23-24,26,32H,4-6,13-15,17,19-22H2,1-3H3,(H,40,41)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	60	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent					Assay Description Chinese hamster ovary (CHO) cells overexpressing soluble guanylate cyclase were generated to test the effect of sGC activators in a cellular context....				US Patent US10550102 (2020) BindingDB Entry DOI: 10.7270/Q2PC34SQ
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