Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Guanylate cyclase soluble subunit alpha-1/beta-1' and Ligand = 'BDBM431011'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Guanylate cyclase soluble subunit alpha-1/beta-1 (Homo sapiens (Human))	BDBM431011 (US10550102, Example 64-8) Show SMILES CCc1c(cnn1-c1cccc(n1)-c1cccc2CC[C@H](Oc3ccc(C4CCN(CC4)S(C)(=O)=O)c(CC)c3)c12)C(O)=O |r| Show InChI InChI=1S/C34H38N4O5S/c1-4-22-20-25(13-14-26(22)23-16-18-37(19-17-23)44(3,41)42)43-31-15-12-24-8-6-9-27(33(24)31)29-10-7-11-32(36-29)38-30(5-2)28(21-35-38)34(39)40/h6-11,13-14,20-21,23,31H,4-5,12,15-19H2,1-3H3,(H,39,40)/t31-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.5	n/a	n/a	n/a	n/a
NOVARTIS AG US Patent					Assay Description Chinese hamster ovary (CHO) cells overexpressing soluble guanylate cyclase were generated to test the effect of sGC activators in a cellular context....				US Patent US10550102 (2020) BindingDB Entry DOI: 10.7270/Q2PC34SQ
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