Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Heat shock protein HSP 90-beta' and Ligand = 'BDBM50379840'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Heat shock protein HSP 90-beta (Homo sapiens (Human))	BDBM50379840 (CHEMBL2011853) Show SMILES Cc1cn(c2CC(C)(C)CC(=O)c12)-c1ccc2cnc(N)nc2c1 Show InChI InChI=1S/C19H20N4O/c1-11-10-23(15-7-19(2,3)8-16(24)17(11)15)13-5-4-12-9-21-18(20)22-14(12)6-13/h4-6,9-10H,7-8H2,1-3H3,(H2,20,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	705	n/a	n/a	n/a	n/a	n/a	n/a
Serenex Inc. Curated by ChEMBL					Assay Description Inhibition of HSP90-mediated Her2 degradation in human AU565 cells after 24 hrs by ELISA				Bioorg Med Chem Lett 22: 2550-4 (2012) Article DOI: 10.1016/j.bmcl.2012.01.137 BindingDB Entry DOI: 10.7270/Q2WQ04TB
					More data for this Ligand-Target Pair