Found 2 hits Enz. Inhib. hit(s) with Target = 'Hematopoietic prostaglandin D synthase' and Ligand = 'BDBM50615774' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Hematopoietic prostaglandin D synthase
(Homo sapiens (Human)) | BDBM50615774
(CHEMBL5273807)Show SMILES COc1ncc2cc(cnc2n1)C(=O)N[C@H]1CC[C@@H](CC1)C(C)(C)O |r,wU:15.16,wD:18.23,(-8.66,-2.59,;-7.32,-3.36,;-5.99,-2.59,;-5.99,-1.07,;-4.68,-.29,;-3.34,-1.06,;-2.02,-.28,;-.68,-1.05,;-.68,-2.59,;-2.01,-3.36,;-3.34,-2.59,;-4.66,-3.36,;.66,-.28,;.66,1.26,;1.99,-1.05,;3.32,-.28,;3.32,1.26,;4.66,2.03,;5.99,1.26,;5.99,-.28,;4.66,-1.05,;7.32,2.03,;6.55,3.36,;8.1,3.36,;8.66,1.26,)| | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 140 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
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More data for this Ligand-Target Pair | |
Hematopoietic prostaglandin D synthase
(Rattus norvegicus) | BDBM50615774
(CHEMBL5273807)Show SMILES COc1ncc2cc(cnc2n1)C(=O)N[C@H]1CC[C@@H](CC1)C(C)(C)O |r,wU:15.16,wD:18.23,(-8.66,-2.59,;-7.32,-3.36,;-5.99,-2.59,;-5.99,-1.07,;-4.68,-.29,;-3.34,-1.06,;-2.02,-.28,;-.68,-1.05,;-.68,-2.59,;-2.01,-3.36,;-3.34,-2.59,;-4.66,-3.36,;.66,-.28,;.66,1.26,;1.99,-1.05,;3.32,-.28,;3.32,1.26,;4.66,2.03,;5.99,1.26,;5.99,-.28,;4.66,-1.05,;7.32,2.03,;6.55,3.36,;8.1,3.36,;8.66,1.26,)| | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |