Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Heme oxygenase 1' and Ligand = 'BDBM50467686'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Heme oxygenase 1 (Rattus norvegicus (rat))	BDBM50467686 (CHEMBL4289670) Show SMILES Cc1ccc(NC(=O)c2ccc(OCCCCn3ccnc3)c(Br)c2)cc1Nc1nccc(n1)-c1cccnc1 Show InChI InChI=1S/C30H28BrN7O2/c1-21-6-8-24(18-27(21)37-30-34-12-10-26(36-30)23-5-4-11-32-19-23)35-29(39)22-7-9-28(25(31)17-22)40-16-3-2-14-38-15-13-33-20-38/h4-13,15,17-20H,2-3,14,16H2,1H3,(H,35,39)(H,34,36,37)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	920	n/a	n/a	n/a	n/a	n/a	n/a
University of Catania Curated by ChEMBL					Assay Description Inhibition of heme oxygenase 1 in Sprague-Dawley rat spleen microsomal fraction assessed as decrease in bilirubin formation using biliverdin reductas...				Eur J Med Chem 158: 937-950 (2018) Article DOI: 10.1016/j.ejmech.2018.09.048 BindingDB Entry DOI: 10.7270/Q2NK3HQ4
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