Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Heme oxygenase 1' and Ligand = 'BDBM50535266'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Heme oxygenase 1 (Rattus norvegicus (rat))	BDBM50535266 (CHEMBL4589369) Show SMILES COc1ccc2[nH]c(=O)c(cc2c1)-c1nc(c([nH]1)-c1ccccc1)-c1ccccc1 Show InChI InChI=1S/C25H19N3O2/c1-30-19-12-13-21-18(14-19)15-20(25(29)26-21)24-27-22(16-8-4-2-5-9-16)23(28-24)17-10-6-3-7-11-17/h2-15H,1H3,(H,26,29)(H,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Catania Curated by ChEMBL					Assay Description Inhibition of HO-1 in Sprague-Dawley rat spleen microsomes using NADPH as substrate incubated for 60 mins by spectrometry based assay				Eur J Med Chem 167: 439-453 (2019) Article DOI: 10.1016/j.ejmech.2019.02.027 BindingDB Entry DOI: 10.7270/Q2P55S0Z
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