Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Heme oxygenase 2' and Ligand = 'BDBM50526846'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Heme oxygenase 2 (Rattus norvegicus (rat))	BDBM50526846 (CHEMBL4559629) Show SMILES Brc1ccc(Cn2c(CC3CC4CCC3C4)nc3ccccc23)cc1 |TLB:8:9:15:12.13| Show InChI InChI=1S/C22H23BrN2/c23-19-9-6-15(7-10-19)14-25-21-4-2-1-3-20(21)24-22(25)13-18-12-16-5-8-17(18)11-16/h1-4,6-7,9-10,16-18H,5,8,11-14H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Catania Curated by ChEMBL					Assay Description Inhibition of Sprague-Dawley rat brain microsome HO-2 preincubated for 10 mins followed by beta-NADPH addition and measured after 15 mins by gas chro...				Eur J Med Chem 183: (2019) Article DOI: 10.1016/j.ejmech.2019.111703 BindingDB Entry DOI: 10.7270/Q2WD441F
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Heme oxygenase 2 (Rattus norvegicus (rat))	BDBM50526846 (CHEMBL4559629) Show SMILES Brc1ccc(Cn2c(CC3CC4CCC3C4)nc3ccccc23)cc1 |TLB:8:9:15:12.13| Show InChI InChI=1S/C22H23BrN2/c23-19-9-6-15(7-10-19)14-25-21-4-2-1-3-20(21)24-22(25)13-18-12-16-5-8-17(18)11-16/h1-4,6-7,9-10,16-18H,5,8,11-14H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Catania Curated by ChEMBL					Assay Description Inhibition of HO-2 in Sprague-Dawley rat brain microsomes using NADPH as substrate preincubated for 10 mins followed by substrate addition and measur...				Eur J Med Chem 167: 439-453 (2019) Article DOI: 10.1016/j.ejmech.2019.02.027 BindingDB Entry DOI: 10.7270/Q2P55S0Z
					More data for this Ligand-Target Pair