Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Hepatic triacylglycerol lipase' and Ligand = 'BDBM187310'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatic triacylglycerol lipase (Homo sapiens (Human))	BDBM187310 (US9169240, 49) Show SMILES NC(=O)NCc1nnc(o1)C(=O)c1nc2ccc(cc2s1)-c1ccccc1 Show InChI InChI=1S/C18H13N5O3S/c19-18(25)20-9-14-22-23-16(26-14)15(24)17-21-12-7-6-11(8-13(12)27-17)10-4-2-1-3-5-10/h1-8H,9H2,(H3,19,20,25)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>10	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human HL expressed in human COS7 cells using A10070 as substrate preincubated for 20 min followed by DMPG vesicle doped substrate addit...				J Med Chem 63: 1660-1670 (2020) Article DOI: 10.1021/acs.jmedchem.9b01831 BindingDB Entry DOI: 10.7270/Q28G8PZS
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