Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Hepatocyte growth factor receptor' and Ligand = 'BDBM100703'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM100703 (US8507676, 51-R | US8507676, 51-S) Show SMILES CC(c1cnc2ccc(nn12)C(\C)=N\OCCO)c1c(F)cc2n(C)ncc2c1F Show InChI InChI=1S/C20H20F2N6O2/c1-11(19-14(21)8-16-13(20(19)22)9-24-27(16)3)17-10-23-18-5-4-15(25-28(17)18)12(2)26-30-7-6-29/h4-5,8-11,29H,6-7H2,1-3H3/b26-12+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.80	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...				US Patent US8507676 (2013) BindingDB Entry DOI: 10.7270/Q2MS3RC9
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM100703 (US8507676, 51-R | US8507676, 51-S) Show SMILES CC(c1cnc2ccc(nn12)C(\C)=N\OCCO)c1c(F)cc2n(C)ncc2c1F Show InChI InChI=1S/C20H20F2N6O2/c1-11(19-14(21)8-16-13(20(19)22)9-24-27(16)3)17-10-23-18-5-4-15(25-28(17)18)12(2)26-30-7-6-29/h4-5,8-11,29H,6-7H2,1-3H3/b26-12+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	460	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...				US Patent US8507676 (2013) BindingDB Entry DOI: 10.7270/Q2MS3RC9
					More data for this Ligand-Target Pair