Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Hepatocyte growth factor receptor' and Ligand = 'BDBM100714'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM100714 (US8507676, 63 | US9062045, Comparator No. 2) Show SMILES CN1CCN(CC1)c1cnc2ccc(Cc3nnc4ccc(nn34)C(\C)=N\OCCO)cc2c1 Show InChI InChI=1S/C24H28N8O2/c1-17(29-34-12-11-33)21-5-6-23-26-27-24(32(23)28-21)14-18-3-4-22-19(13-18)15-20(16-25-22)31-9-7-30(2)8-10-31/h3-6,13,15-16,33H,7-12,14H2,1-2H3/b29-17+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-F...				US Patent US9062045 (2015) BindingDB Entry DOI: 10.7270/Q23F4NDS
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM100714 (US8507676, 63 | US9062045, Comparator No. 2) Show SMILES CN1CCN(CC1)c1cnc2ccc(Cc3nnc4ccc(nn34)C(\C)=N\OCCO)cc2c1 Show InChI InChI=1S/C24H28N8O2/c1-17(29-34-12-11-33)21-5-6-23-26-27-24(32(23)28-21)14-18-3-4-22-19(13-18)15-20(16-25-22)31-9-7-30(2)8-10-31/h3-6,13,15-16,33H,7-12,14H2,1-2H3/b29-17+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...				US Patent US8507676 (2013) BindingDB Entry DOI: 10.7270/Q2MS3RC9
					More data for this Ligand-Target Pair