Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Hepatocyte growth factor receptor' and Ligand = 'BDBM100718'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM100718 (US8507676, 67) Show SMILES C\C(=N/OCCO)c1cnc2ccc(Cn3nnc4ncc(nc34)C(\C)=N\OCCO)cc2c1 Show InChI InChI=1S/C22H24N8O4/c1-14(27-33-7-5-31)18-10-17-9-16(3-4-19(17)23-11-18)13-30-22-21(26-29-30)24-12-20(25-22)15(2)28-34-8-6-32/h3-4,9-12,31-32H,5-8,13H2,1-2H3/b27-14+,28-15+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...				US Patent US8507676 (2013) BindingDB Entry DOI: 10.7270/Q2MS3RC9
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