Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Hepatocyte growth factor receptor' and Ligand = 'BDBM100725'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM100725 (US8507676, 76-S) Show SMILES C[C@H](c1nnc2ccc(nn12)C(\C)=N\OCC1CC1)c1c(F)cc2ncccc2c1F |r| Show InChI InChI=1S/C22H20F2N6O/c1-12(20-16(23)10-18-15(21(20)24)4-3-9-25-18)22-27-26-19-8-7-17(28-30(19)22)13(2)29-31-11-14-5-6-14/h3-4,7-10,12,14H,5-6,11H2,1-2H3/b29-13+/t12-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...				US Patent US8507676 (2013) BindingDB Entry DOI: 10.7270/Q2MS3RC9
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