Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Hepatocyte growth factor receptor' and Ligand = 'BDBM2214'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM2214 (US8507676, 53-S) Show SMILES C[C@H](c1nnc2ccc(nn12)C(\C)=N\OCCO)c1c(F)cc2ncccc2c1F |r| Show InChI InChI=1S/C20H18F2N6O2/c1-11(18-14(21)10-16-13(19(18)22)4-3-7-23-16)20-25-24-17-6-5-15(26-28(17)20)12(2)27-30-9-8-29/h3-7,10-11,29H,8-9H2,1-2H3/b27-12+/t11-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.5	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The kinase assay is based on the LanthaScreen technology. LanthaScreen is the detection of Time-Resolved Fluorescence Resonance Energy Transfer (TR-...				US Patent US8507676 (2013) BindingDB Entry DOI: 10.7270/Q2MS3RC9
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