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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Hepatocyte growth factor receptor' and Ligand = 'BDBM50235557'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50235557
PNG
(1-(4-(5-((3-aminopropylamino)methyl)pyrrolo[1,2-f]...)
Show SMILES NCCCNCc1ccn2ncnc(Oc3ccc(NC(=O)NC(=O)Cc4ccc(F)cc4)cc3F)c12
Show InChI InChI=1S/C25H25F2N7O3/c26-18-4-2-16(3-5-18)12-22(35)33-25(36)32-19-6-7-21(20(27)13-19)37-24-23-17(14-29-10-1-9-28)8-11-34(23)31-15-30-24/h2-8,11,13,15,29H,1,9-10,12,14,28H2,(H2,32,33,35,36)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 1.40E+3n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of human c-MET


Eur J Med Chem 46: 3675-80 (2011)


Article DOI: 10.1016/j.ejmech.2011.05.031
BindingDB Entry DOI: 10.7270/Q2891676
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50235557
PNG
(1-(4-(5-((3-aminopropylamino)methyl)pyrrolo[1,2-f]...)
Show SMILES NCCCNCc1ccn2ncnc(Oc3ccc(NC(=O)NC(=O)Cc4ccc(F)cc4)cc3F)c12
Show InChI InChI=1S/C25H25F2N7O3/c26-18-4-2-16(3-5-18)12-22(35)33-25(36)32-19-6-7-21(20(27)13-19)37-24-23-17(14-29-10-1-9-28)8-11-34(23)31-15-30-24/h2-8,11,13,15,29H,1,9-10,12,14,28H2,(H2,32,33,35,36)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 1.40E+3n/an/an/an/an/an/a



Bristol-Myers Squibb Research and Development

Curated by ChEMBL


Assay Description
Inhibition of human recombinant c-Met expressed in insect cell-baculovirus expression system


Bioorg Med Chem Lett 18: 1945-51 (2008)


Article DOI: 10.1016/j.bmcl.2008.01.121
BindingDB Entry DOI: 10.7270/Q2125SFV
More data for this
Ligand-Target Pair