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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Hepatocyte growth factor receptor' and Ligand = 'BDBM50384128'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50384128
PNG
(CHEMBL2029686)
Show SMILES COCCOc1cnc2ccc(cc2c1)[C@H](C)n1nnc2ccn(-c3cc(F)cc(F)c3)c(=O)c12 |r|
Show InChI InChI=1S/C25H21F2N5O3/c1-15(16-3-4-22-17(9-16)10-21(14-28-22)35-8-7-34-2)32-24-23(29-30-32)5-6-31(25(24)33)20-12-18(26)11-19(27)13-20/h3-6,9-15H,7-8H2,1-2H3/t15-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1n/an/an/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Inhibition of c-Met


Bioorg Med Chem Lett 22: 4089-93 (2012)


Article DOI: 10.1016/j.bmcl.2012.04.072
BindingDB Entry DOI: 10.7270/Q2J67HZ2
More data for this
Ligand-Target Pair
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM50384128
PNG
(CHEMBL2029686)
Show SMILES COCCOc1cnc2ccc(cc2c1)[C@H](C)n1nnc2ccn(-c3cc(F)cc(F)c3)c(=O)c12 |r|
Show InChI InChI=1S/C25H21F2N5O3/c1-15(16-3-4-22-17(9-16)10-21(14-28-22)35-8-7-34-2)32-24-23(29-30-32)5-6-31(25(24)33)20-12-18(26)11-19(27)13-20/h3-6,9-15H,7-8H2,1-2H3/t15-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3n/an/an/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Inhibition of HGF-induced autophosphorylation of c-Met in human PC3 cells


Bioorg Med Chem Lett 22: 4089-93 (2012)


Article DOI: 10.1016/j.bmcl.2012.04.072
BindingDB Entry DOI: 10.7270/Q2J67HZ2
More data for this
Ligand-Target Pair